Endocrine Abstracts

Objective: To evaluate the impact of different modes of insulin therapy (continuous subcutaneous insulin infusion (CSII) using insulin pump or multiple insulin injections (MII)) on carbohydrate metabolism, the state of the transplant, cardiovascular system, calcium and phosphorus metabolism in patients with type 1 diabetes (DM1) during the 1st year after kidney transplantation (KT).Materials and methods: The study included patients with DM1 after transpl...

Aim: The aim of study is to investigate the effects of renal pathology on the cardiovascular system in patients with T1D, the detection of the most important cardiovascular risk factors associated with CKD.Methods: The study includes 156 patients with a long duration of T1D (more than 20 years): 24 patients without CKD, 82 patients with 1–4 stages of CKD, 29 patients on hemodialysis, 21 patients after kidney transplantation. In addition to the routi...

Aim: The aim of study is to investigate the effects of renal pathology on the cardiovascular system in patients with T1D, the detection of the most important cardiovascular risk factors associated with CKD.Methods: The study includes 156 patients with a long duration of T1D (more than 20 years): 24 patients without CKD, 82 patients with 1–4 stages of CKD, 29 patients on hemodialysis, 21 patients after kidney transplantation. In addition to the routi...

Objective: To evaluate the simultaneous pancreas–kidney transplantation (SPK) effect on stabilisation/progression of complications in patients with T1DM.Materials and methods: The study included 16 patients after SPK. Eleven peoples received standard triple immunosuppressive therapy during the study period, five patients canceled steroid therapy after 6 months. The average age was 34 years old (31; 40), duration of T1DM 22 years (20.5; 28), the dura...

Aims: To estimate the nonglycaemic effects of incretins in patients with long history of type 1 diabetes (T1D) and chronic kidney disease (CKD).Materials and methods: We examined 75 patients with a long history T1D (more than 20 years) and CKD on the different stages: 32 patients with CKD at the stages 1–4, 17 patients on haemodialysis, 11 with kidney transplantation, and 15 patients without CKD. In addition to routine methods of investigation we ha...